The Bioactive
Peptide Library

A comprehensive clinical index of research compounds, including mechanisms of action, pharmacokinetic data, and safety profiles.

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Researcher’s Guide to Peptide Science

Navigating the world of peptide therapeutics requires a solid understanding of biochemistry, pharmacokinetics, and regulatory classes. Below is a primer on how to interpret the data presented in this library.

1. Nomenclature & Classification

Peptide naming conventions can be confusing. Names often describe the origin, the function, or the sequence length.

  • Fragments: Snipped sections of a larger parent hormone to isolate specific effects.
  • Analogues: Synthetic versions with amino-acid substitutions to improve stability/potency.
  • Secretagogues: Stimulate release of another hormone (signal the body to produce it).

2. Understanding Pharmacokinetics (PK)

The “Half-Life” listed in the cards helps estimate dosing frequency needed to maintain levels.

Short Half-Life (< 1 hr): More “pulsatile” exposure.

Long Half-Life (> 24 hrs): More stable exposure, often less frequent administration.

3. Mechanism Classes

PathwayActionExamples
GHRH Amplifies GH release per pulse. CJC-1295, Sermorelin, Tesamorelin
Ghrelin / GHS Increases pulse frequency. Ipamorelin, MK-677, Hexarelin
Synergy Combining pathways can be additive. CJC-1295 + Ipamorelin

4. Reconstitution Math Primer

Concentration = Mass / Volume. Example: 5mg + 2mL → 2.5mg/mL.

For dosing math, use the Peptide Dosage Calculator.